Update README.md

README.md

@@ -21,7 +21,7 @@ The BioEM software computes this integral via numerical grid sampling over a por
 By comparing the BioEM posterior probabilities it is possible to discriminate and rank structural models, allowing to characterize
 the variability and dynamics of the biological system.
 
-See the BioEM_Maunal.pdf for a detailed description of the BioEM software.
+For a detailed description of the BioEM software see the BioEM_Maunal.pdf that is provided in the Manual directory.
 
 ### Command line input & help is found by just running the compiled executable ./bioEM